Two hundred years after Mary Shelley's novel the brilliant but mad Doctor (Thomas Kretschmann) has sustained his creature and himself over two centuries through genetic experimentation. In present-day America Detective O'Connor (Parker Posey) is investigating a series of horrific murders which leads her to the doctor a…

故事开端于1955年的纽约布鲁克林区，哈里·安格尔（米基·洛克 饰）是个胡子不剃、一直吸烟的私人侦察，专门查询拜访离婚案。一天，一个自称叫路易斯·赛佛雷（罗伯特·德尼罗 饰）的神孤本国人找到了他，要他往寻觅一个叫弗沃里特的嘉赞家。这项任务钱很多，看起来也很放松，哈里就接收了。 可是，哈里在查询拜访中发明，本人所打仗的每个与这…