来自南承平洋萨摩亚群岛的体育记者杜克（约翰尼·德普 Johnny Depp 饰）和他的律师同伙刚佐博士（本尼西奥·德·托尔 Benicio Del Tore 饰）一起开车前往拉斯维加斯，寻觅他们的“美国梦”。一起上，他们带了大批毒品和酒精，也碰到形形色色的人，药物劝化下，许多迷乱和癫狂的画面出现，让他们分不清幻觉和实际，到底哪个更残破，哪个更肮脏扭…
A Native American grandmother who lives very simply alone in the desert actually inhabits a world that her half-Hispanic grandson and an aging white magician are surprised to rediscover.
A suburban woman fights to be believed as she finds herself stalked by a threatening figure who returns to her house night after night. When she can't get help from those around her, she is forced to take matters into her own hands.
